PPM - Cytogenetic Analysis of Newly Diagnosed Acute Leukemia (AML, A-ALL, P-ALL)
Version: November 2025
Description:
This module provides an overview of new recommendations for the cytogenomic laboratory workup of patients with newly diagnosed acute leukemia. Laboratory Directors are asked to select 10 consecutive cases of newly diagnosed acute leukemia—including acute myeloid leukemia (AML), adult acute lymphoblastic leukemia (A-ALL), and pediatric acute lymphoblastic leukemia (P-ALL)—for whom they reported results on in the last two years. For each case, please answer the following 20 questions regarding the case workup. Answer choices will be “yes,” “no,” or “not applicable.” At the end of the activity, you will be asked four additional questions assessing your overall performance on this module.
Scroll to the bottom of this page for a Preview of the Checklist.
Practice Performance Modules (CCP Part IV)
(Continuing Certification Program was formerly the Maintenance of Certification Program (MOC)
Practice performance modules are derived from accepted practice guidelines related to genetics patient care. Modules are available for pediatric genetics, adult genetics and prenatal/obstetric genetic care providers.
Process:
- Educational Content – Review module, literature, and practice checklist
- Charting – Review 10 consecutive charts with patients newly diagnosed acute lukemia for whom you reported results in the past two years.
- Assesment and Self-Reflection
- Evaluation
Completion of these modules should be based on actual patient care as documented in your patient chart. The process is not meant to be punitive but designed to help assess practice and facilitate practice improvement. The modules should be completed honestly based on documentation in the chart. An audit process may be implemented by ACMG to document compliance. Learners should keep track of the specific charts used to complete the practice module so that these charts could be reproduced in the setting of an audit.
Self-reflections should be meaningful and provide evidence that the diplomate has considered the practice guidelines contained in the exercise in the context of their own clinical practice. Answers to reflection questions should be 2-3 full sentences long and have thoughtful content. Answers to reflection questions will be anonymized and reviewed for content by the MOC committee. Reflections that do not meet these guidelines will be returned to the diplomate for revision. Revisions that do not meet guidelines may result in forfeiture of MOC credit for a given module and a request to repeat the module.
- Do you think this module reflects best practice? Please elaborate whether you agree or disagree and state why.
- Did you identify any gaps in your practice? If so, please elaborate.
- If you identified gaps in your practice, what changes do you plan make to your practice based on this module?
- What if any barriers do you foresee for implementing change if you identified gaps in your practice? For example, short staffing, time factors etc.
