Knowledge Nugget Series

The ACMG ACT Sheets are a clinical decision support tool to help non-genetics providers understand more about specific genetic conditions found through genetic screening or testing. To make these excellent one-page resources a more active educational resource, NCC published Knowledge Nuggets for specific ACMG ACT Sheets. Each Knowledge Nugget is five to nine minutes and provides an animated walk-through of the ACMG ACT Sheet. Click on the one of the conditions below to access the modules and associate materials.

To access the video for non-CME credit, please visit https://nccrcg.org/knowledge-nugget-series/

Amino Acidemias- Elevated Citrulline Knowledge Nugget

Biotinidase Deficiency Knowledge Nugget

Carnitine Palmitoyltransferase II (CPT II) Deficiency Knowledge Nugget

Classic Galactosemia Knowledge Nugget

GAMT Knowledge Nugget

Glutaric Acidemia Type 1 Knowledge Nugget

Glutaric Acidemia Type 2 ACT Sheet

Long-Chain 3-Hydroxyacyl-CoA Dehydrogenase Deficiency (LCHAD Deficiency) Knowledge Nugget

Isovaleric Acidemia Knowledge Nugget

MCAD Knowledge Nugget

MPS I Knowledge Nugget

MPS II Knowledge Nugget

Organic Acidemias: Elevated C5-OH Acylcarnitine Knowledge Nugget

PAH Knowledge Nugget

Phenylalanine Hydroxylase (PAH) Deficiency Knowledge Nugget

Pompe Disease Knowledge Nugget

Primary or Secondary HyperGalactosemia Knowledge Nugget

Propionic Acidemia Knowledge Nugget

Very Long-Chain Acyl-CoA Dehydrogenase (VLCAD) Deficiency Knowledge Nugget

This project is supported by the Health Resources and Services Administration (HRSA) of the U.S. Department of Health and Human Services (HHS) under Cooperative Agreement #UH9MC30770 from 6/2020-5/2024 for $800,000 per award year.