
2025 ClinGen Somatic Cancer and VICC Virtual Molecular Tumor Board Case Series
Course Description
This course explores the clinical significance of germline and somatic variants in cancer and provides practical knowledge on the application of clinical guidelines and bioinformatics tools for treatment recommendations. Participants will gain an understanding of how various disciplines—medical oncology, molecular pathology, genomics, bioinformatics, and genetic counseling—collaborate in cancer care. Emphasizing the importance of multi-institutional collaboration, the course covers workflows for cancer variant interpretation, including the utilization of genomic tumor boards and variant annotation pipelines.
Target Audience
All medical and healthcare professionals and researchers interested in understanding cancer genomic testing and somatic and germline variant interpretation methods. This series is presented as a collaboration between ClinGen Somatic, VICC, and ACMG consortia.
Webinar Series
January 28, 2025
Title: Cases in Precision Oncology: Highlights from the 2024 ClinGen Somatic Cancer and VICC Virtual Molecular Tumor Board Case Series
February 25, 2025
Title: Chromosomal Mimicry in Hematologic Malignancies
March 25, 2025
Title: Complementary Use of Circulating Tumor Cell Sequencing and Tumor Sequencing
Apri 22, 2025
Title: TBA
May 27, 2025
Title: TBA
June 24, 2025
Title: TBA
Learning Objectives
At the conclusion of this series, participants should be able to:
• Apply clinical guidelines and bioinformatics tools to determine the clinical significance of germline and somatic variants in cancer
• Describe the spectrum of resources to aid in cancer variant interpretation in the clinic
• Utilize genomic tumor boards informed by multiple workflows and annotation pipelines