Practice Exam-Cell Biology Genomics

Cell Biology Genomics

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The document consists of two practice exam questions on topics related to cell biology and genomics, authored by Claudia Barnett. <br /><br />The first question (ID 25219) revolves around a female patient with a genetic condition involving the X chromosome. The patient possesses a normal X chromosome and an isochromosome for the q arm of the X chromosome. An isochromosome is characterized by the loss of one arm and the duplication of the other, leading to monosomy for one arm and trisomy for the other arm. In this context, the patient has an isochromosome Xq, resulting in monosomy for the Xp arm and trisomy for the Xq arm. The correct answer to the question is option C: "Monosomic for Xp and trisomic for Xq."<br /><br />The second question (ID 25218) asks which statement does not relate to centromeres. The statements include characteristics and functions typically associated with centromeres, such as the 171 bp tandemly repeated DNA sequence (option A), alpha-satellite sequence (option B), chromosome-specific FISH probes based on sequence divergence (option C), and being targeted by spindle microtubules during mitosis (option E). However, statement D, "Shortens with age," does not relate to centromeres; instead, it describes a characteristic of telomeric repeats. Thus, the answer is option D.<br /><br />These questions test knowledge on chromosome anomalies and specific genomic features involving centromeres and telomeres.

Keywords

cell biology

genomics

Claudia Barnett

X chromosome

isochromosome

monosomy

trisomy

centromeres

telomeres

genetic condition